Journal of Rehabilitation Research Current Updates
Dual Viral Assault: Unraveling the Complexities of Dengue and Hepatitis E Co-Infection in a Tropical Setting - "A Case Report"
Abstract
Manjeeta Nath Das, Sahil and Shivam Sharma
Background: Dengue fever and hepatitis E are distinct viral infections endemic to tropical and subtropical regions. Both conditions share overlapping clinical features, such as fever, jaundice, and liver dysfunction. However, co-infection with these viruses is rare and poses significant diagnostic and management challenges. This case report highlights the clinical complexity, diagnostic workup, and management of a patient with dengue and hepatitis E co-infection.
Case Presentation: A 35-year-old male from North Indian presented with fever and extreme weakness for three days. On examination, he had mild hepatomegaly and icterus. Laboratory investigations revealed thrombocytopenia, hyperbilirubinemia, and markedly elevated transaminases. Serology confirmed dengue (NS1 antigen positive) and hepatitis E (IgM positive). The patient was managed conservatively with supportive care, including intravenous fluids and hepatoprotective medications. His condition gradually improved, and he was discharged in stable condition after clinical and biochemical recovery.
Conclusions: This case underscores the importance of considering co-infections in febrile illnesses with liver dysfunction in endemic regions. Early diagnosis and comprehensive supportive care are vital in preventing complications and ensuring recovery.

