Journal of Global Traditional Medicine and Indigenous Healing Systems
Bridging Ancestral Wisdom and Digital Flow: A CFD Frame-work for Optimizing Traditional Drug Delivery Via Droplet Dy-namics
Abstract
Mohammad Yaghoub Abdollahzadeh Jamalabadi
The integration of modern computational techniques with traditional medicine systems offers unprecedented opportunities to optimize drug delivery while preserving the holistic principles of indigenous healing practices. This study presents a computational fluid dynamics (CFD) model of a capillary-based drug delivery system, simulating the transport of a therapeutic agent into a moving aqueous droplet as it traverses a permeable membrane. The axisymmetric two-phase flow model incorporates laminar flow, moving mesh methodology, and diluted species transport to characterize drug diffusion and convection dynamics under varying droplet velocities (0.1–1.0 mm/s). Results demonstrate that the total drug dose delivered is approximately inversely proportional to droplet velocity, with an “S-shaped” accumulation profile over time. The model successfully captures complex flow patterns at the droplet interface and concentration gradients within the droplet, providing quantitative insights into parameters governing drug uptake efficiency. This framework establishes a foundation for applying computational modeling to the rational design and optimization of traditional medicine delivery systems, bridging ancestral knowledge with contemporary pharmaceutical engineering.