Nanomedicine and Nanoscience Technology: Open Access
Computational Predicton of Compounds Toxicity for Resistance Mechanism Discovery in Anopheles Gambiae
Abstract
Falade Emmanuel Eniola and Marion Adebiyi
This research computationally identifies, evaluate and analysis the related proteins and pathways of Anopheles Gambia and Homo Sapiens and their reactions to chemical compounds, and it studies the toxicity to help determine chemical compositions for corresponding proteins targets for insecticides formulations, to determine the compounds structure of chemicals that has unique reaction for Anopheles Gambiae only. This research aims at providing unique information on Anopheles Gambiae checkpoint for further studies and also to draw attentions to compounds that may have little or no toxic effect on Homo Sapiens. This study confirms that some Chemicals compounds compositions have unique reactions for Anopheles Gambiae only.