Journal of Molecular Genetics and Gene Research
Genomics and Oscc Cure
Abstract
Dr. Amruta Sheth
Oral Squamous Cell Carcinoma (OSCC) is a highly heterogeneous malignancy characterized by complex molecular alterations that cannot be fully understood through single-omics approaches. Multi-omics integration, encompassing genomics, proteomics, and metabolomics, provides a comprehensive framework for understanding tumor biology and therapeutic vulnerabilities. Genomics identifies driver mutations, proteomics elucidates functional protein networks, and metabolomics captures metabolic reprogramming essential for tumor survival. Integrative analysis enables improved biomarker discovery, identification of novel drug targets, and prediction of therapeutic response. “This paper presents a theoretical analysis of literature-derived data to examine advances in multi-omics approaches in Oral Squamous Cell Carcinoma and their implications for Targeted therapy, Immunotherapy and drugs resistance.”