Journal of Molecular Genetics and Gene Research

Evolutionary Genetics

Pharmacogenetics is the branch of pharmacology that examines the relation of genetic factors to variations in response to drugs. There are various factors contributing to the interindividual variability of treatments and this chapter discusses the contribution of genetic variation to interindividual variability. Pharmacogenetics utilizes in fact available genetic technologies to study a limited number of genes to characterize the molecular basis of the individual response to drugs, while pharmacogenomics involves the study of the whole genome (DNA) or its products (RNAs) as they relate to drug response utilizing high-throughput technologies characteristic of this science.

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