Nanomedicine and Nanoscience Technology: Open Access

Department of Biotechnology, Mersin University, Mersin, Turkey

Publications

• Research   
  Bismuth Oxide Nanoparticle: The Potential of Apoptotic and Genetic Damage on MDBK Cell Line
  Author(s): Asawir Esamaldeen Ebrahim Mohamed, Ayla Celik* and Derya Yetkin
  
  Nowadays, nanoparticles have been used in almost all areas of life thanks to advances in nano scale technology. Among the available nanoparticles, Bismuth oxide nanoparticle is widely used in many products in terms of its properties such as antibacterial, antitumor and cytotoxic activity and antifungal. In this study, we aimed to determine the in vitro genetic damage potential and apoptotic effects of bismuth oxide nanoparticle having 90-210 nm size (~191,2 nm) range in MDBK cell line cultures. In this study; single cell gel electrophoresis (comet) method and flow cytometry method were used to determine genotoxic and apoptotic effect. The MDBK (Madin Darby Bovine Kidney) cells were treated with bismuth oxide at three concentrations of 30 µg/ml, 60 µg/ml and 90 µg/ml. No significant difference was found between the negative control group for GDI and DCP parameter (p&g.. Read More»
  

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