Reviews in Pharmacy and Pharmaceutical Sciences

Department of Chemistry and Pharmacy, Rani Durgavati University, India

Publications

• Research Article   
  Computational Approach for Designing, Swiss ADME, Molecular Docking and Biological Implication of Nickel Based Transition Metal Complex
  Author(s): Mohd. Washid Khan*, Nihal Pillai, Abhishek Pandey, Priyanka Mihaulia, Shubham Singh and Sakshi Swami
  
  In this article was showing a computational approach to statistical learning gives a novel introduction to predictive modeling by focusing on the algorithmic and numeric motivations behind popular statistical methods. In this approach using Swiss ADME web tools for evaluate biophysical parameter like lipophilicity, drug likeness, water solubility and medicinal chemistry of nickel base metal complex data was showing through tabular form. Furthermore, molecular docking study of all compounds was performed against enzymes and DNA DISCOVERY STUDIO 2021 after confirmation of DNA-interaction through docking studies, nuclease activity was performed using agarose gel electrophoresis method and all compounds have been found to cleave DNA. These results concluded that nickel complexes of sulfonamide may be good induction in the future for medical purposes... Read More»
  

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