Reviews in Pharmacy and Pharmaceutical Sciences

Chromatography

Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid (gas or solvent) called the mobile phase, which carries it through a system (a column, a capillary tube, a plate, or a sheet) on which a material called the stationary phase is fixed. The different constituents of the mixture have different affinities for the stationary phase. The different molecules stay longer or shorter on the stationary phase, depending on their interactions with its surface sites. So, they travel at different apparent velocities in the mobile fluid, causing them to separate. The separation is based on the differential partitioning between the mobile and the stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.

Relevant Articles

Research Article

Feasibility Study of Transesophago-Tracheal Ventilation in a Beagle Dog

  • Weihua Xu, Jieqiong Wang, Haidong He, Ming Chen and Linghe Luo
DOI: 10.66311/3069-4310.02.01.05

Research Article

Antibacterial Activity and Gc-Ms Analysis of Gouania Longispicata Eng. Root Extract Against Bacterial Pathogens

  • Diriba Borena Hunde, Zelalem Abdissa, Wakshume Adugna, Negera Abdissa, Chaltu File and Desalegn Borena

Research Article

Pharmacogenetic Implications in the Clinical Approach to Antiretroviral Therapy. a Systematic Review

  • Geysson Orlando Rico-Lezcano, Luis Abel Quiñones and Nelson Miguel Varela
DOI: 10.66311/3069-4310.02.01.01

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